Research for ENT,Head and Neck Surgery

Learn more about research within ENT, Head and Neck Surgery.

The Otolaryngology Head and Neck Surgery Department has a commitment to high level evidenced-based clinical practice, continuing professional development and research. The collective expertise of our dynamic team is considerable with a high publication profile in high impact medical journals and textbooks. We are well-recognised nationally and internationally for clinical and research activities across the field with regular invitations to present and contribute to specialty conferences. Our primary research initiatives involve the investigation and translation of cutting edge technology and new scientific knowledge to disease control, patient well-being, quality of life and optimal functional outcomes in voice, swallowing, hearing and breathing.

We will continue to expand our research capabilities and stimulate new avenues for advancement in the delivery of clinical care and improved outcomes. We are affiliated with Monash University and our growing post-graduate research team is involved in various translational research topics, especially in the head and neck cancer, rhinology and laryngology areas. We welcome genuine expressions of interest from prospective PhD or Master of Philosophy students who are keen to join our research activities and pursue a higher degree.

Contact information

Head of Department

Associate Professor Debbie Phyland,
ENT Clinical Research Director

Department Publications

2020

Hu, Y., Teh, B. M., Hurtado, G., Yao, X., Huang, J., & Shen, Y. (2020). Can endoscopic ear surgery replace microscopic surgery in the treatment of acquired cholesteatoma? A contemporary review. International Journal of Pediatric Otorhinolaryngology, 109872.

Huang, J., Teh, B. M., Eikelboom, R. H., Han, L., Xu, G., Yao, X., … & Shen, Y. (2020). The Effectiveness of bFGF in the Treatment of Tympanic Membrane Perforations: A Systematic Review and Meta-Analysis. Otology & Neurotology.

Phyland, D. J., & Vallance, N. A. (2020). The Young Aspiring Singer. In Multidisciplinary Management of Pediatric Voice and Swallowing Disorders (pp. 465-476). Springer, Cham.

Leong, P., Ruane, L. E., Phyland, D., Koh, J., MacDonald, M. I., Baxter, M., … & Bardin, P. G. (2020). Inspiratory vocal cord closure in chronic obstructive pulmonary disease. European Respiratory Journal.

Vella, B., Brown, L., & Phyland, D. (2020). Amateur Music Theatre Singers’ Perceptions of their Current Singing Voice Function. Journal of Voice.

2019

Yi Wong, D. J., & Paddle, P. (2019). Harmonic scalpel versus other techniques for tonsillectomy: a systematic review and meta-analysis. Australian Journal of Otolaryngology, 2.

Alwan, M., Phyland, D., Pudel, E., Booth, E., & Vallance, N. (2019). Long term self-reported post-operative outcomes of endoscopic and open pharyngeal pouch repairs. Australian Journal of Otolaryngology, 2.

Alwan, M., & Hurtado, G. (2019). Unilateral permanent sudden sensorineural hearing loss after spina-epidural anaesthesia for caesarean section: a case report. Journal of Surgical Case Reports, 2019(12), rjz316.

Baxter, M., Ruane, L., Phyland, D., Leahy, E., Heke, E., Lau, K. K., … & Bardin, P. G. (2019). Multidisciplinary team clinic for vocal cord dysfunction directs therapy and significantly reduces healthcare utilization. Respirology, 24(8), 758-764.

Bhullar, H. K., Aung, A. K., Graudins, L., Ihle, J., Gin, D., Cleland, H., & Teh, B. M. (2019). Upper airway involvement in Stevens–Johnson syndrome and toxic epidermal necrolysis. Burns.

Casswell, G., Cavanagh, K., Kumar, A. S. R., Giddings, C., & McDowell, L. (2019). Setting the stage: Contemporary staging of non-melanomatous skin cancer and implementation of the new American Joint Committee on cancer eighth edition staging manual. Oral Oncology, 98, 102-108.

Douglas, R. G., Psaltis, A. J., Rimmer, J., Kuruvilla, T., Cervin, A., & Kuang, Y. (2019, April). Phase 1 clinical study to assess the safety of a novel drug delivery system providing long‐term topical steroid therapy for chronic rhinosinusitis. In International forum of allergy & rhinology (Vol. 9, No. 4, pp. 378-387).

Kovacs, A., Haran, S., & Paddle, P. (2019). Chronic non-granulomatous supraglottitis of a male adolescent and its successful management with azathioprine. BMJ Case Reports CP, 12(4), e227458.

Lam, M. E., Woods, C. M., Du, C., Milton, T., Kao, S. S. T., Huynh, J., Sigston, E. & Ooi, E. H. (2019). Outcomes using the T-14 symptom score for tonsillectomy in an Australian paediatric population. Australian Journal of Otolaryngology, 2.

O’Loughlin, C. J., Phyland, D. J., Vallance, N. A., Giddings, C., Malkoutzis, E., Gunasekera, E., … & Barnes, R. (2019). Low‐flow apnoeic oxygenation for laryngeal surgery: a prospective observational study. Anaesthesia.

Page, D. E., Rimmer, J., Keane, M., Manikappa, S., Butzbach, D., & Giddings, C. (2019). Is atomised intranasal cocaine systemically absorbed during endoscopic sinus surgery?. Rhinology, 57(3), 200-205.

Phyland, D. J. (2019). Choral Singing and Vocal Health—Young Choristers Are Not Harming by Harmonizing. JAMA Otolaryngology–Head & Neck Surgery, 145(5), 451-452.

Phyland, D., & Miles, A. (2019). Occupational voice is a work in progress: active risk management, habilitation and rehabilitation. Current opinion in otolaryngology & head and neck surgery, 27(6), 439-447.

Rotman, A., Kerr, S. J., & Giddings, C. E. (2019). Elective neck dissection in metastatic cutaneous squamous cell carcinoma to the parotid gland: A systematic review and meta‐analysis. Head & neck, 41(4), 1131-1139.

Speyer, R., Kim, J. H., Doma, K., Chen, Y. W., Denman, D., Phyland, D., … & Cordier, R. (2019). Measurement properties of self-report questionnaires on health-related quality of life and functional health status in dysphonia: a systematic review using the COSMIN taxonomy. Quality of Life Research, 28(2), 283-296.

Tescher, A. L., Ahmadi, N., & Teh, B. M. (2019). The prophylactic use of antibiotics in submandibular gland excision: an audit and review of risk factors. Australian Journal of Otolaryngology, 2.

Tran, A. H., Horne, R. S., Liew, D., Rimmer, J., & Nixon, G. M. (2019). An epidemiological study of paediatric adenotonsillectomy in Victoria, Australia, 2010‐2015: Changing indications and lack of effect of hospital volume on inter‐hospital transfers. Clinical Otolaryngology, 44(6), 1037-1044.

Woliansky, J., Paddle, P., & Phyland, D. (2019). Laryngotracheal Stenosis Management: A 16-Year Experience. Ear, Nose & Throat Journal, 0145561319873593.

Woliansky, J., Phyland, D., & Paddle, P. (2019). Systemic safety of serial intralesional steroid injection for subglottic stenosis. The Laryngoscope, 129(7), 1634-1639.

2018

Franco Jr, R. A., Husain, I., Reder, L., & Paddle, P. (2018). Awake serial intralesional steroid injections without surgery as a novel targeted treatment for idiopathic subglottic stenosis. The Laryngoscope, 128(3), 610-617.

Kwok, M. M., Wong, A., Paddle, P., Goergen, S., & Rimmer, J. (2018). Clinico-radiological predictors of positive rigid bronchoscopy findings in children with suspected tracheobronchial foreign body aspiration. Australian Journal of Otolaryngology, 1(2).

Lee, J. W., Tay, T. R., Paddle, P., Richards, A. L., Pointon, L., Voortman, M., … & Hew, M. (2018). Diagnosis of concomitant inducible laryngeal obstruction and asthma. Clinical & Experimental Allergy, 48(12), 1622-1630.

Wong, D. J., Donaldson, C., Lai, L. T., Coleman, A., Giddings, C., Slater, L. A., & Chandra, R. V. (2018). Safety and effectiveness of endovascular embolization or stent‐graft reconstruction for treatment of acute carotid blowout syndrome in patients with head and neck cancer: Case series and systematic review of observational studies. Head & neck, 40(4), 846-854.

2017

Joosten, S. A., Leong, P., Landry, S. A., Sands, S. A., Terrill, P. I., Mann, D., Burgess, G, Hayes, A.. & Mansfield, D. (2017). Loop gain predicts the response to upper airway surgery in patients with obstructive sleep apnea. Sleep, 40(7), zsx094.

Kwok, M. M. K., & Paddle, P. (2017). Median philtrum sinus: a rare presentation and review of management options. Case Reports, 2017.

Lim, R. S., Evans, L., George, A. P., De Alwis, N., Stimpson, P., Merriel, S., … & Sigston, E. (2017). Do demographics and tumour-related factors affect nodal yield at neck dissection? A retrospective cohort study. The Journal of Laryngology & Otology, 131(S1), S36-S40.

Lund, V. J., Darby, Y., Rimmer, J., Amin, M., & Husain, S. (2017). Nasal closure for severe hereditary haemorrhagic telangiectasia in 100 patients. The Lund modification of the Young’s procedure: a 22-year experience. Rhinology, 55(2), 135-141.

McLean, T., Kerr, S. J., & Giddings, C. E. (2017). Prophylactic dissection of level V in primary mucosal SCC in the clinically N positive neck: A systematic review. The Laryngoscope, 127(9), 2074-2080.

Paddle, P., Husain, I., McHugh, L., & Franco Jr, R. (2017). Outcomes of mechanical stapling for postlaryngectomy open pharyngotomy closure. The Laryngoscope, 127(3), 605-610.

Perju-Dumbrava, L., Lau, K., Phyland, D., Papanikolaou, V., Finlay, P., Beare, R., … & Thyagarajan, D. (2017). Arytenoid cartilage movements are hypokinetic in Parkinson’s disease: A quantitative dynamic computerised tomographic study. PloS one, 12(11).

Phyland, D. (2017). The Measurement and Effects of Vocal Load in Singing Performance. How Much Singing Can a Singer Sing if a Singer Can Sing Songs?. Perspectives of the ASHA Special Interest Groups, 2(3), 79-88.

Sigston, E. A., & Williams, B. R. (2017). An emergence Framework of Carcinogenesis. Frontiers in Oncology, 7, 198.

Tan, C. H., Chan, F., Rimmer, J., & Goldschlager, T. (2017). A young girl with headache and partial ptosis. Journal of Clinical Neuroscience, 43, 278-280.

Wong, D. J. Y., Stanley, P., & Paddle, P. (2017). Laryngeal cryptococcosis associated with inhaled corticosteroid use: case reports and literature review. Frontiers in surgery, 4, 63.

2016

Amini, E., Rorke, S., & Uren, B. (2016). Sinonasal epithelial-myoepithelial carcinoma: A case report. Pathology, 48, S64-S65.

Hew, M., Gillman, A., Sutherland, M., Wark, P., Bowden, J., Guo, M., … & Rimmer, J. (2016). Real‐life effectiveness of omalizumab in severe allergic asthma above the recommended dosing range criteria. Clinical & Experimental Allergy, 46(11), 1407-1415.

Lim, R. S., Ramdave, S., Beech, P., Billah, B., Karim, M. N., Smith, J. A., … & Sigston, E. (2016). Utility of SUV max on 18 F-FDG PET in detecting cervical nodal metastases. Cancer Imaging, 16(1), 39.

Rimmer, J., Amin, M., Fokkens, W. J., & Lund, V. J. (2016). Endoscopic sinus surgery and musculoskeletal symptoms. Rhinology, 54(2), 105-10.

Sigston, E. A., Longano, A., Strzelecki, A. T., & Williams, B. R. (2016). Surgical margins in head and neck squamous cell carcinoma: Effect of heat artifact on immunohistochemistry as a future tool for assessment. Head & neck, 38(9), 1401-1406.

Stokes, P. J., & Rimmer, J. (2016). The relationship between serum Vitamin D and chronic rhinosinusitis: A systematic review. American journal of rhinology & allergy, 30(1), 23-28.

Wong, A. S., Teh, B. M., & Safdar, A. (2016). The absent facial nerve pes anserinus: implications for parotid surgery. ANZ journal of surgery, 86(12), 1067-1068.

2015

Serpell, J., Sidhu, S., Vallance, N., Panizza, B., & Randolph, G. (2015). Re: Consensus statements in surgery: intra‐operative neural monitoring for thyroid surgery. ANZ Journal of Surgery, 85(4), 294-294.

Young, R. J., Urban, D., Angel, C., Corry, J., Lyons, B., Vallance, N., … & Rischin, D. (2015). Frequency and prognostic significance of p16INK4A protein overexpression and transcriptionally active human papillomavirus infection in laryngeal squamous cell carcinoma. British Journal of Cancer, 112(6), 1098-1104.

2014

Baxter, M., Uddin, N., Raghav, S., Leong, P., Low, K., Hamza, K., … & Bardin, P. G. (2014). Abnormal vocal cord movement treated with botulinum toxin in patients with asthma resistant to optimised management. Respirology, 19(4), 531-537.

Lim, A. M., Do, H., Young, R. J., Wong, S. Q., Angel, C., Collins, M., Sigston, E. … & Solomon, B. (2014). Differential mechanisms of CDKN2A (p16) alteration in oral tongue squamous cell carcinomas and correlation with patient outcome. International Journal of Cancer, 135(4), 887-895.

Khoo, J. F., Batt, M., Stimpson, P., & Safdar, A. (2014). Supraglottic immunoglobulin‐G4 related plasma cell granuloma: Case report and literature review. Head and Neck, 36(6), E57-E59.

Phyland, D. J., Pallant, J. F., Thibeault, S. L., Benninger, M. S., Vallance, N., & Smith, J. A. (2014). Measuring Vocal Function in Professional Music Theater Singers: Construct Validation of the Evaluation of the Ability to Sing Easily (EASE). Folia Phoniatrica et Logopaedica, 66(3), 100-108.

Stimpson, P., Batt, M., & Vallance, N. (2014). Head and neck cancer recurrence: a prospective analysis of 401 follow‐up visits to an Australian cancer centre. Clinical Otolaryngology, 39(5), 292-296.

Shilton, H., Hodgson, M., & Burgess, G. (2014). Hyperbaric oxygen therapy for sudden sensorineural hearing loss in large vestibular aqueduct syndrome. The Journal of Laryngology & Otology, 128(S1), S50-S54.

Aw, H. C., Suen, L. W., Christopher, F. D., Longano, A., Mahanta, V., & Vallance, N. (2014). Cervical Langerhans cell histiocytosis (histiocytosis X). ANZ Journal of Surgery.

Ruane, L. E., Lau, K. K., Low, K., Crossett, M., Vallance, N., & Bardin, P. G. (2014). Dynamic 320‐slice CT larynx for detection and management of idiopathic bilateral vocal cord paralysis. Respirology Case Reports, 2(1), 24-26.

2013

Kel, G., Tan, J., Eastwood, H., Wongprasartsuk, S . & O’Leary, S. (2013) Early cochlear response and ICAM-1 expression to cochlear implantation. Otology and Neurotology, 34 (9): 1575-1602

Phyland, D. J., Pallant, J. F., Benninger, M. S., Thibeault, S. L., Greenwood, K. M., Smith, J. A., & Vallance, N. (2013). Development and preliminary validation of the EASE: a tool to measure perceived singing voice function. Journal of Voice, 27(4), 454-462.

Baxter, M., Tan, K. F., Harney, M., & Suen, K. (2013). Otogenic Intracranial Abscesses: A Case Series. Journal of Case Reports, 3(2), 413-418.

Lin, R.T., Wongprasartsuk, S., Bhimrao, S.K. & Westerberg, B.D. Otologic and Neurotologic Manifestations of Human Immunodeficiency Virus. Encyclopaedia of Otolaryngology Head and Neck Surgery (Ed S Koutakis) 2013. Springer USA.

Phyland, D. J., Thibeault, S. L., Benninger, M. S., Vallance, N., Greenwood, K. M., & Smith, J. A. (2013). Perspectives on the impact on vocal function of heavy vocal load among working professional music theater performers. Journal of Voice, 27(3), 390-e31.

Marshall, K. L., Baxter, M., & Leech, M. (2013). Myeloperoxidase Positive Wegener’s Granulomatosis with Isolated Otorhinological Involvement. Journal of Case Reports, 3(2), 291-194.

Truong An, P. & Sigston, E. (2013). Schwannoma of the Palatine Tonsil: A Rare Entity in an Eight Year Old Girl. Journal of Clinical & Experimental Oncology.

Young, R. J., Lim, A. M., Angel, C., Collins, M., Deb, S., Corry, J, Sigston, E., … & Solomon, B. (2013). Frequency of Fibroblast Growth Factor Receptor 1 gene amplification in oral tongue squamous cell carcinomas and associations with clinical features and patient outcome. Oral Oncology, 49(6), 576-581.

2012

Mianroodi, A. A., Teimouri, Y., & Vallance, N. A. (2012). Foreign bodies: Aspirated or ingested? A report of two unusual cases. Iranian Journal of Otorhinolaryngology, 24(67), 91.

Pham, T. A., De Freitas, R., Young, G., & Safdar, A. (2012). Laryngeal paraganglioma in an irradiated neck. The Journal of Laryngology & Otology, 126(07), 747-750.

Pham, T. A., De Freitas, R., Sigston, E., & Vallance, N. (2012). Factors leading to the use of alternate treatment modalities following transoral laser excision of T1 and T2 glottic squamous cell carcinoma. ANZ Journal of Surgery, 82(10), 720-723.

Souter, M., Eastwood, H., Marovic, P., Kel, G., Wongprasartsuk, S. , Ryan, A. & O’Leary, S. (2012) Systemic immunity influences hearing preservation in cochlear implantation. Otology and Neurotology, 33(4):532-538

2011

Low, K., Lau, K. K., Holmes, P., Crossett, M., Vallance, N., Phyland, D., … & Bardin, P. G. (2011). Abnormal vocal cord function in difficult-to-treat asthma. American Journal of Respiratory and Critical Care Medicine, 184(1), 50-56.

Pudel, E. (2011). The role of panendoscopy in head and neck cancer: is it still required? British Journal Anaesthesia, 106, 617-31.

Corry, J., Rischin, D., Cotton, S., D’Costa, I., Chua, M., Vallance, N., … & Peters, L. J. (2011). Larynx preservation with primary non‐surgical treatment for loco‐regionally advanced larynx cancer. Journal of Medical Imaging and Radiation Oncology, 55(2), 229-235.

2010

Wongprasartsuk, S. , Danks, A. & Vallance, N. (2010) Ear Nose and Throat, Head and Neck Problems. In Hunt & Marshall’s Clinical Problems in Surgery: 2nd edition (eds Julian A. Smith,, Jane G. Fox, Alan C. Saunderm & Ming Kon Yii) ch 2

2009

Holmes, P. W., Lau, K. K., Crossett, M., Low, C., Buchanan, D., Hamilton, G. S., & Bardin, P. G. (2009). Diagnosis of vocal cord dysfunction in asthma with high resolution dynamic volume computerized tomography of the larynx. Respirology, 14(8), 1106-1113.

Roth, J. A., Sigston, E., & Vallance, N. (2009). Endoscopic stapling of pharyngeal pouch: A 10-year review of single versus multiple staple rows. Otolaryngology–Head and Neck Surgery, 140(2), 245-249.

2008

Babin, E., Sigston, E., Hitier, M., Dehesdin, D., Marie, J. P., & Choussy, O. (2008). Quality of life in head and neck cancers patients: predictive factors, functional and psychosocial outcome. European Archives of Oto-rhino-laryngology, 265(3), 265-270.

O’Leary, S., & Vallance, N. (2008) Otorhinolaryngology. In Textbook of Surgery, Third Edition, (eds JJ Tjandra, GJA Clunie, AH Kaye, JA Smith) ch 38; 323-331.

2006

Arabi Mianroodi, A. A., Sigston, E. A., & Vallance, N. A. (2006). Frozen section for parotid surgery: should it become routine?. ANZ Journal of Surgery, 76(8), 736-739.

Benninger, M. S., Grywalski, C., Phyland, D., Johnson, A., & Jacobson, B. (2006). Rehabilitation of head and neck cancer patients. In Medical speech language pathology: A practitioner’s guide. Ch12.

Vallance, N. (2006) Epistaxis. In Textbook of Surgery, Third Edition, (eds JJ Tjandra, GJA Clunie, AH Kaye, JA Smith), ch 28.

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