Monash Health stroke research: $5 million national study to transform stroke recovery

Monash Health researchers have secured $5 million in federal funding for a major study into stroke recovery, in a project they say could help identify new treatments and improve care for patients across the country.

Six researchers stand together for a group photo in an office setting.
Left to right: Dr John Ly, Prof Henry Ma, Prof Connie Wong, Dr Shu Wen Wen, Dr Jenny Wilson and Dr Jason Vuong.

The IMAGINE study also involves collaborators at hospitals across Australia. 

Researchers will track stroke patients over time, combining data on proteins, molecules and gene activity with brain imaging, clinical assessments and information on complications such as recurrent stroke and infection. 

The team says bringing these different types of data together, an approach known as multiomics, should help them better understand what happens in the brain and body during stroke recovery, and why some patients recover better than others. 

They hope the findings will point to new treatment targets, speed up the development of new drugs, and lead to better rehabilitation programs. The large datasets generated by the study will also be used to train artificial intelligence tools designed to predict patient outcomes and help health services plan more effectively for future demand. 

‘What truly sets IMAGINE apart is its extensive database that integrates individual multi-level biomarkers with comprehensive clinical assessments over time and multivariate analysis of imaging data,’ said Professor Henry Ma, Director of Monash Health’s Neurology Department.  

‘This innovative system not only advances precision medicine to new heights but also generates valuable insights capable of influencing health outcomes and survivorship.’ 

Researchers say the project builds on a run of recent National Health and Medical Research Council (NHMRC) and Medical Research Future Fund (MRFF) grants awarded to Monash Health neurologists and reflects a broader push to strengthen the hospital’s research partnership with Monash University. 

 

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Monash Health stroke research: $5 million national study to transform stroke recovery