David Sheffield

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David Sheffield

MBBS (Hons) BMedSci (Hons) (Monash) FRACP PhD (Monash)

Infectious Diseases Physician
Physician, Refugee Health Service

ARC Centre of Excellence in Structural and Functional Microbial Genomics, Monash University

The PTEN and Myotubularin Phosphoinositide 3-Phosphatases: Linking Lipid Signalling to Human Disease.
Leslie NR, Davies EM, Sheffield DA, Tibarewal P, Fedele CG, Mitchell CA.
Subcell Biochem. 2012;58:281-336.

Silencer of death domains (SODD) inhibits skeletal muscle and kidney enriched inositol phosphatase (SKIP) and regulates phosphoinositide 3-kinase (PI3K)/Akt signalling to the actin cytoskeleton.
Rahman P, Huysmans RD, Wiradjaja F, Gurung R, Ooms LM, Sheffield DA, Dyson JM, Layton MJ, Sriratana A, Takada H, Tiganis T, Mitchell CA.
J Biol Chem. 2011 Jun 28. [Epub ahead of print]
PMID: 21712384 [PubMed – as supplied by publisher] Free Article

The myotubularin phosphatase MTMR4 regulates sorting from early endosomes.
Naughtin MJ, Sheffield DA, Rahman P, Hughes WE, Gurung R, Stow JL, Nandurkar HH, Dyson JM, Mitchell CA.
J Cell Sci. 2010 Sep 15;123(Pt 18):3071-83. Epub 2010 Aug 24.
PMID: 20736309 [PubMed – as supplied by publisher]

Regulation of PI(3)K/Akt signalling and cellular transformation by inositol polyphosphate 4-phosphatase-1.
Ivetac I, Gurung R, Hakim S, Horan KA, Sheffield DA, Binge LC, Majerus PW, Tiganis T, Mitchell CA.
EMBO Rep. 2009 May;10(5):487-93. Epub 2009 Mar 27.
PMID: 19325558 [PubMed – indexed for MEDLINE]Free PMC ArticleFree text

Characterisation of PfRON6, a Plasmodium falciparum rhoptry neck protein with a novel cysteine-rich domain.
Proellocks NI, Kats LM, Sheffield DA, Hanssen E, Black CG, Waller KL, Coppel RL.
Int J Parasitol. 2009 May;39(6):683-92. Epub 2008 Nov 27.
PMID: 19073187 [PubMed – indexed for MEDLINE]

Differential occurrence of mutations in mitochondrial DNA of human skeletal muscle during aging.
Zhang C, Liu VW, Addessi CL, Sheffield DA, Linnane AW, Nagley P.
Hum Mutat. 1998;11(5):360-71. Erratum in: Hum Mutat 1998;12(1):69.
PMID: 9600454 [PubMed – indexed for MEDLINE