Staphylococcal Infection

Learn more about Staphylococcal infections below.

Clinical Studies

Completed

Publications

Low rates of endocarditis in healthcare-associated Staphylococcus aureus bacteraemia suggest echocardiography is not always required.
Barton T, Moir S, Rehmani H, Woolley I, Korman TM, Stuart RL.
Eur J Clin Microbiol Infect Dis 2015 [in press]

Peripheral intravenous catheter-associated Staphylococcus aureus bacteraemia: more than 5 years of prospective data from two tertiary health services.
Stuart RL, Cameron DRM, Scott C, Kotsanas D, Grayson ML, Korman TM, Elizabeth E Gillespie EE, Johnson PDR.
Med J Aust 2013;198(10):551-3.PMID: 23725270 [PubMed – in process]

Vancomycin AUC/MIC and 30-day mortality in patients with Staphylococcus aureus bacteremia.
Holmes NE, Turnidge JD, Munckhof WJ, Robinson JO, Korman TM, O’Sullivan MV, Anderson TL, Roberts SA, Warren SJ, Gao W, Howden BP, Johnson PD.
Antimicrob Agents Chemother. 2013 Apr;57(4):1654-63. doi: 10.1128/AAC.01485-12. Epub 2013 Jan 18.
PMID: 23335735 [PubMed – as supplied by publisher]

Vancomycin minimum inhibitory concentration, host comorbidities and mortality in Staphylococcus aureus bacteraemia.
Holmes NE, Turnidge JD, Munckhof WJ, Robinson JO, Korman TM, O’Sullivan MV, Anderson TL, Roberts SA, Warren SJ, Gao W, Johnson PD, Howden BP.
Clin Microbiol Infect 2013 Feb 26. doi: 10.1111/1469-0691.12168. [Epub ahead of print]

The Dominant Australian Community-Acquired Methicillin-Resistant Staphylococcus aureus Clone ST93-IV [2B] Is Highly Virulent and Genetically Distinct.
Chua KYL, Seemann T, Harrison PF, Monagle S, Korman TM, Johnson PD, Coombs GW, Howden BO, Davies JK, Howden BP, Stinear TP.
PLoS One. 2011;6(10):e25887. doi: 10.1371/journal.pone.0025887. Epub 2011 Oct 3.
PMID:21991381 [PubMed – indexed for MEDLINE] Free PMC Article

Methicillin-Susceptible Staphylococcus aureus Endocarditis Isolates Are Associated With Clonal Complex 30 Genotype and a Distinct Repertoire of Enterotoxins and Adhesins.
Nienaber JJ, Sharma Kuinkel BK, Clarke-Pearson M, Lamlertthon S, Park L, Rude TH, Barriere S, Woods CW, Chu VH, Marín M, Bukovski S, Garcia P, Corey GR, Korman T, Doco-Lecompte T, Murdoch DR, Reller LB, Fowler VG Jr; for the International Collaboration on Endocarditis-Microbiology Investigators.
J Infect Dis. 2011 Sep;204(5):704-713.
PMID: 21844296 [PubMed – as supplied by publisher]

Antibiotic choice may not explain poorer outcomes in patients with high vancomycin MIC Staphylococcus aureus bacteremia.
Holmes NE. Turnidge JD. Munchkof WJ. Robinson JO. Korman TM. O’Sullivan MVN. Anderson TL. Roberts SA. Gao W. Christiansen KJ. Coombs GW. Johnson PDR. Howden BP.
J Infect Dis. 2011 Aug;204(3):340-7.
PMID: 21742831 [PubMed – in process]

Heterogeneous vancomycin-intermediate susceptibility phenotype in bloodstream methicillin-resistant Staphylococcus aureus isolates from an international cohort of patients with infective endocarditis: prevalence, genotype, and clinical significance.
Bae IG, Federspiel JJ, Miró JM, Woods CW, Park L, Rybak MJ, Rude TH, Bradley S, Bukovski S, de la Maria CG, Kanj SS, Korman TM, Marco F, Murdoch DR, Plesiat P, Rodriguez-Creixems M, Reinbott P, Steed L, Tattevin P, Tripodi MF, Newton KL, Corey GR, Fowler VG Jr; International Collaboration on Endocarditis-Microbiology Investigator.
J Infect Dis. 2009 Nov 1;200(9):1355-66.
PMID: 19811099 [PubMed – indexed for MEDLINE]

Genotypic diversity of coagulase-negative staphylococci causing endocarditis: a global perspective.
Petti CA, Simmon KE, Miro JM, Hoen B, Marco F, Chu VH, Athan E, Bukovski S, Bouza E, Bradley S, Fowler VG, Giannitsioti E, Gordon D, Reinbott P, Korman T, Lang S, Garcia-de-la-Maria C, Raglio A, Morris AJ, Plesiat P, Ryan S, Doco-Lecompte T, Tripodi F, Utili R, Wray D, Federspiel JJ, Boisson K, Reller LB, Murdoch DR, Woods CW; International Collaboration on Endocarditis-Microbiology Investigators.
J Clin Microbiol. 2008 May;46(5):1780-4. Epub 2008 Mar 26.
PMID: 18367572 [PubMed – indexed for MEDLINE] Free PMC Article Free text

A clonal outbreak of rifampicin-resistant methicillin-resistant Staphylococcus aureus (MRSA) in an intensive care unit.
Friedman ND, Kotsanas D, Wilson J, Ten Berk de Boer F, Korman T.
Aust Infect Control. 2006; 11(2):53-8.

Poor specificity of screening tests for the detection of Staphylococcus aureus with reduced susceptibility to vancomycin.

Friedman ND, Midolo PD, Kotsanas D, Korman T.
Int J Infect Control. 2006; 2:98-101.

Community and health-care associated non-multiresistant methicillin-resistant Staphylococcus aureus in Victoria.
Howden BP, Grabsch EA, King H, Graham M, Johnson PD, Korman TM, Grayson ML, Mayall BC.
Med J Aust. 2005 Nov 21;183(10):548. No abstract available.
PMID: 16296982 [PubMed – indexed for MEDLINE] Free Article

Treatment outcomes for serious infections caused by methicillin-resistant Staphylococcus aureus with reduced vancomycin susceptibility.
Howden BP, Ward PB, Charles PG, Korman TM, Fuller A, du Cros P, Grabsch EA, Roberts SA, Robson J, Read K, Bak N, Hurley J, Johnson PD, Morris AJ, Mayall BC, Grayson ML.
Clin Infect Dis. 2004 Feb 15;38(4):521-8. Epub 2004 Jan 29.
PMID: 14765345 [PubMed – indexed for MEDLINE]

Laboratory detection and investigation of reduced susceptibility to vancomycin in oxacillin-resistant Staphylococcus aureus.
Midolo PD, Korman TM, Kotsanas D, Russo P, Kerr TG.
Eur J Clin Microbiol Infect Dis. 2003 Mar;22(3):199-201. Epub 2003 Mar 5. No abstract available.
PMID: 12649722 [PubMed – indexed for MEDLINE

The clinical efficacy of continuous-infusion flucloxacillin in serious staphylococcal sepsis.
Leder K, Turnidge JD, Korman TM, Grayson ML.
J Antimicrob Chemother. 1999 Jan;43(1):113-8.
PMID: 10381108 [PubMed – indexed for MEDLINE] Free Article