Hepatitis C Research

Discover more about our Hepatitis C research.

Clinical Trials

Completed

• BMS-790052 (Hepatitis C-HIV coinfection)

Publications

The two-edged sword: vasculitis associated with HIV and Hepatitis C coinfection.
Ojaimi S, Lin MW, Singh KP, Woolley I
Int J STD AIDS 2013 Jul 25. [Epub ahead of print]
PMID:23970639 [PubMed – as supplied by publisher]

The role of natural killer cells in hepatitis C infection.
Howell J, Visvanathan K.
Antivir Ther. 2013 Apr 4. doi: 10.3851/IMP2565. [Epub ahead of print]
PMID: 23559549 [PubMed – as supplied by publisher]

Toll-Like Receptors in Hepatitis C Infection: Implications for Pathogenesis and Treatment.
Howell J, Angus P, Gow P, Visvanathan K.
J Gastroenterol Hepatol. 2013 Feb 22. doi: 10.1111/jgh.12170. [Epub ahead of print]
PMID:23432473 [PubMed – as supplied by publisher]

Toll-Like Receptor 3 and 7/8 Function Is Impaired in Hepatitis C Rapid Fibrosis Progression Postliver Transplantation.
Howell J, Sawhney R, Skinner N, Gow P, Angus P, Ratnam D, Visvanathan K.
Am J Transplant. 2013 Feb 20. doi: 10.1111/ajt.12165. [Epub ahead of print]
PMID:23425350 [PubMed – as supplied by publisher]

Clinical Implications of the Innate and Adaptive Immune Response to HBV and HCV.
Le ST, Visvanathan K.
Curr Hepatitis Rep 2012;11:243-249.

Polymorphisms of Toll-like receptors and their pathways in viral hepatitis.
Sawhney R, Visvanathan K.
Antivir Ther. 2011;16(4):443-58.
PMID: 21685532 [PubMed – in process]

Acute allograft rejection in human liver transplant recipients is associated with signaling through toll-like receptor 4.
Testro AG, Visvanathan K, Skinner N, Markovska V, Crowley P, Angus PW, Gow PJ.
J Gastroenterol Hepatol. 2011 Jan;26(1):155-63. doi: 10.1111/j.1440-1746.2010.06324.x.
PMID: 21175809 [PubMed – in process]

Hepatic TLR2 & TLR4 expression correlates with hepatic inflammation and TNF-α in HCV & HCV/HIV infection.
Berzsenyi MD, Roberts SK, Preiss S, Woollard DJ, Beard MR, Skinner NA, Bowden DS, Visvanathan K.
J Viral Hepat. 2010 Nov 3. doi: 10.1111/j.1365-2893.2010.01390.x. [Epub ahead of print]
PMID: 21050341 [PubMed – as supplied by publisher]

Effects of antibiotics on expression and function of Toll-like receptors 2 and 4 on mononuclear cells in patients with advanced cirrhosis.
Testro AG, Gow PJ, Angus PW, Wongseelashote S, Skinner N, Markovska V, Visvanathan K.
J Hepatol. 2010 Feb;52(2):199-205. Epub 2009 Dec 16.
PMID: 20006396 [PubMed – indexed for MEDLINE]

Toll-like receptors and their role in gastrointestinal disease.
Testro AG, Visvanathan K.
J Gastroenterol Hepatol. 2009 Jun;24(6):943-54. Review.
PMID: 19638078 [PubMed – in process]

Characterization of the innate immune signalling pathways in hepatocyte cell lines.
Preiss S, Thompson A, Chen X, Rodgers S, Markovska V, Desmond P, Visvanathan K, Li K, Locarnini S, Revill P.
J Viral Hepat. 2008 Dec;15(12):888-900. Epub 2008 Jul 28.
PMID: 18673429 [PubMed – indexed for MEDLINE]

Synbiotic-associated improvement in liver function in cirrhotic patients: Relation to changes in circulating cytokine messenger RNA and protein levels.
Riordan SM, Skinner NA, McIver CJ, Liu Q, Bengmark S, Bihari D, Visvanathan K.
Microb Ecol Health Dis. 2007;19(1):7-16.

Toll-like receptor expression in chronic hepatitis C: correlation with pro-inflammatory cytokine levels and liver injury.
Riordan SM, Skinner NA, Kurtovic J, Locarnini S, McIver CJ, Williams R, Visvanathan K.
Inflamm Res. 2006 Jul;55(7):279-85.
PMID: 16955390 [PubMed – indexed for MEDLINE]

Immunopathogenesis: role of innate and adaptive immune responses.
Visvanathan K, Lewin SR.
Semin Liver Dis. 2006 May;26(2):104-15. Review.
PMID: 16673289 [PubMed – indexed for MEDLINE]

Peripheral blood mononuclear cell expression of toll-like receptors and relation to cytokine levels in cirrhosis.
Riordan SM, Skinner N, Nagree A, McCallum H, McIver CJ, Kurtovic J, Hamilton JA, Bengmark S, Williams R, Visvanathan K.
Hepatology. 2003 May;37(5):1154-64.
PMID: 12717397 [PubMed – indexed for MEDLINE]

Hepatitis C and pregnancy: an update.
Giles M, Hellard M, Sasadeusz J.
Aust N Z J Obstet Gynaecol. 2003 Aug;43(4):290-3. Review.
PMID: 14714713 [PubMed – indexed for MEDLINE]