Research and education
Current clinical projects
General neurosurgery
- SAVES-N: A prospective adverse event reporting system for neurosurgical cases.
- Relationship between sleep quality and surgical aptitude in neurosurgical trainees
- Artificial Intelligence for the Prediction and Evolutionary Modelling of Chronic Subdural Haematoma Progression
- The EVACUATE Trial: A Prospective, Multicentre, Randomised Controlled Study Comparing Ultra-Early Minimally Invasive Intracerebral Haemorrhage Evacuation Versus Standard Treatment
- QOL in Decompressive Craniectomy
- Review of the impact of Blockchain technology on Neurosurgery in the future
- Risk stratification and outcomes prediction in patients using applied machine learning and natural language processing
- Neurosurgery in the Tropics
- The upskilling of general surgeons in performing emergency neurosurgery in rural and remote Australia
- Australasian Shunt Registry Database
- Subdural Database (Chronic)
Cerebrovascular
- A Prospective Analysis of Treatment Outcomes and Prognostic Factors in Aneurysmal Subarachnoid Haemorrhage
- Impact of Time-to-Treatment on Functional and Neurological Outcomes in Aneurysmal Subarachnoid Haemorrhage: A Retrospective Cohort Study
- Surgical Outcomes and Risk Stratification in the Management of Unruptured Anterior Communicating Artery Aneurysms: A Contemporary Institutional Review
- Surgical Management and Outcome Determinants in Unruptured Posterior Communicating Artery Aneurysms: A Contemporary Analysis
- Risk of Rupture in Small Cerebral Aneurysms: A Retrospective Cohort Study Investigating Haemorrhagic Potential and Clinical Predictors
- Postoperative Seizure Risk Following Elective Craniotomy for Intracranial Aneurysm Treatment: A Retrospective Analysis
- Natural History of Small Incidental Intracranial Aneurysms: A Systematic Review and Meta[1]Analysis of Follow-Up Duration and Aneurysm Location as Determinants of Rupture Risk
- Development and Validation of a Novel Grading System for Predicting Intraoperative Rupture Risk During Aneurysm Surgery
- Multicentre Retrospective Validation of a Predictive Grading System for Postoperative Ischaemia Following Middle Cerebral Artery Aneurysm Surgery
- Microsurgical Resection Versus Preoperative Embolisation in Brain Arteriovenous Malformations: A Meta-Analysis Stratified by Spetzler-Martin Grade
- Assessing the Predictive Accuracy of Spetzler-Martin and Supplemented Spetzler-Martin Grading Systems in Brain AVM Microsurgery: A Single-Centre Retrospective Study
- Multidimensional Analysis of Brain Arteriovenous Malformations: Clinical, Imaging, and Treatment Outcome Correlations
- Early Versus Delayed Therapeutic Intervention in Ruptured Brain Arteriovenous Malformations: A Comparative Outcome Study
- Natural History and Haemorrhage Risk of Brain Cavernous Malformations: A Systematic Review and Meta-Analysis
- Surgical Versus Conservative Management of Brainstem Cavernomas: A Comparative Outcome Study
- Clinical Course of Contrast-Induced Neurotoxicity in Neurointervention: Multicentre Nationwide Experience
- Review of Stem cells as a therapy for Ischemic stroke (focus on homing molecules)
- Comparison of flow diverter versus flow diverter with endo-luminal adjunct (Coils/WEB).
- Cerebrovascular prospective database
- Review of Stem cells as a therapy for Ischemic stroke (focus on homing molecules)
- Moya moya disease natural history study
- Systematic review on single vs double barrel bypass in moya moya disease
- Cranial and spinal dural arteriovenous fistulae- retrospective and prospective audit.
Neuro-oncology
- Arcuate fasciculus cortico-cortical and axono-cortical evoked potentials as biomarkers of post-operative language function in supratentorial glioma: systematic review & case series
- Brain tumour database
- Systematic Review in Cervical Vagal Schwannomas
- Monash Live-Biobanking & Precision Cancer Immunotherapy (MoLBi-PCI): From Bench to Precision Therapies
- Does using intraoperative fluorescent imaging improve resection outcomes
- Are patients with brain tumours satisfied with the care they have received, a mixed method study (retro/pro)
- What is a patient’s quality of life following brain tumour treatment (prospective)
- Does the molecular profile of a brain tumour affect the extent of resection?
- Identifying inmmuno peptide targets for development of novel T cell therapies in brain tumours
- UVFSS scores – Endoscopic vs Transcranial for Tuberculum Meningioma
Skull base
- A multicentre prospective registry for endoscopic skull base surgery for the management of pituitary and skull base tumours- Outcome assessment and quality
- Functional Near-Infrared Spectroscopy (fNIRS) for Objective Assessment of Tinnitus in Patients with Acoustic Neuroma: A Pilot Study
- Tumour Size Versus Volume as Predictors of Facial Nerve and Hearing Preservation Following Retrosigmoid Craniotomy for Acoustic Neuroma Resection: A 10-Year Institutional Review
- A Phase 1, Open-Label, Prospective Randomised Controlled Trial Assessing the Feasibility and Safety of Decompression for Unilateral Pulsatile Tinnitus
Spine
- A Multi-Centre, Prospective, Parallel Group, Randomized, Pilot Study Evaluating Safety And Preliminary Effectiveness Of NB1 Bone Graft In Subjects With Degenerative Disc Disease Undergoing Transforaminal Lumbar Interbody Fusion
- Factors affecting low back pain and its impact on sleep quality
- Longitudinal observational study on sleep parameters in patient with chronic back pain.
- Prospective multi-centre trial on the relationship between post-operative activity and outcome in patients undergoing lumbar microdiscectomy.
- Pilot study assessing safety and efficacy of a novel scaffold combined with allogeneic mesenchymal stem cells implanted at the time of microdiscectomy.
- Segmental correction in minimally invasive spine surgery
- RELIEVE Study
- MTRON Fraility study
- Repair Strategies for Spinal CSF leaks with intracranial hypotension
Functional
- Cognitive and Psychiatric Sequelae of Long-Term Anticonvulsant Therapy in Trigeminal Neuralgia: A Prospective Neuropsychological Evaluation
- Machine Learning in Trigeminal Neuralgia: Development and Validation of an AI Algorithm Utilising Radiomic MRI Features for Severity Classification and Treatment Response Prediction
- Facial Pain Database
- Volumetric analysis of Meckel’s cave and the foramen ovale- its relationship to outcomes of balloon compression
Paediatric neurosurgery
- Paediatric Spina Bifida treatment outcomes
- Cerebrovascular Paediatric Database
Publications 2024/25
Cerebrovascular
- Incidence of contrast-induced neurotoxicity following endovascular treatment of unruptured intracranial aneurysms: a single-centre cohort study; Frederick P. Mariajoseph, Leon Lai, Justin Moore, Ronil V Chandra, Tony Goldschalger, Adrian Praeger, Daniel Yu & Lee- Anne Slater; Acta Neurologica Belgica Published: 26 September 2024;Volume 124, pages 1989–1994
- Microsurgery alone versus preoperative embolisation: A meta-analysis of outcomes in brain AVMs by Spetzler-Martin grade; Cyrus Raki, Lily Davies, Leon T Lai; Journal of Clinical Neuroscience, Volume 136, April 2025
- The Australian Diagnostic Criteria for Contrast-Induced Encephalopathy; Frederick P Mariajoseph, Leon T Lai, Adrian Praeger, Ronil V Chandra, Justin Moore, Hamed Asadi, Laetitia de Villiers, Tony Goldschlager, Calvin Gan, Kevin Zhou, Albert Ho Yuen Chiu, Ferdinand Miteff, Ramon Martin Banez, Thanh Phan, Davor Pavlin-Premrl, Winston Chong, Sophie Dunkerton, Anoop Madan, Lee-Anne Slater; Neuroradiology 1-7,Published: 29 March 2025
- Development of a predictive grading system for postoperative ischemia following middle cerebral artery aneurysm clipping; Leon Lai a b, Naquiya Murtaza Mohsin a, Hayder Al-Farttoosi, Cyrus Raki b, Tarundeep Dhaliwal; Journal of Clinical Neuroscience, Volume 130, December 2024.
- Neuroradiological features of contrast-induced neurotoxicity: A systematic review and pooled analysis; Frederick P. Mariajoseph a b, Daniel Yu b, Leon T. Lai a b, Justin Moore a b, Tony Goldschlager a b, Ronil V. Chandra c d, Adrian Praeger a b, Lee-Anne Slater; Journal of Clinical Neuroscience, Volume 126, August 2024, Pages 108-116.
- Clinical management of contrast-induced neurotoxicity: a systematic review;Frederick P Mariajoseph, Jia Xi Chung, Leon T Lai, Justin Moore, Tony Goldschlager, Ronil V Chandra, Adrian Praeger, Lee-Anne Slater; Acta Neurologica Belgica Published: 08 February 2024 Volume 124, pages 1141–1149, (2024)
- Pathophysiology of Contrast-Induced Neurotoxicity: A Narrative Review of Possible Mechanisms; Frederick P. Mariajoseph;Leon Lai;Justin Moore;Ronil Chandra;Tony Goldschlager;Adrian J. Praeger;Lee-Anne Slater; European Neurology Volume 87, Issue 1 March 2024.
Skull Base surgery
- Headache relief following endoscopic drainage of Rathke’s cleft cyst;Annie Jian, Yi Yuen Wang, Tony Goldschlager, Mendel Castle-Kirszbaum, Jeremy Kam, Yi Chen Zhao & James King; Pituitary, Published: 13 March 2025 Volume 28, article number 40, (2025)
- Frailty and pituitary surgery: a systematic review; Mendel Castle-Kirszbaum, Ann McCormack, Christopher Ovenden, Jeremy Kam, James King, Yi Yuen Wang, Tony Goldschlager;Pituitary, Published: 17 March 2025 Volume 28, article number 43, (2025)
- The curious case of headaches and Rathke’s cleft cysts;Hani J. Marcus, Sabrina Chiloiro & Tony Goldschlager; Pituitary, Published: 26 December 2024, Volume 28, article number 6, (2025).
- Quality of life in non-functioning pituitary adenoma: A systematic review; Mendel Castle-Kirszbaum, Ann McCormack, Jeremy Kam, James King, Yi Yuen Wang, Tony Goldschlager; Neurosurgical review, Published: 23 November 2024 Volume 47, article number 867, (2024)
- Impact of sella floor reconstruction on Rathke Cleft Cyst recurrence: a systematic review and meta-analysis; Ryan Beerling Dolovac,James Alexander John King,Christopher Ovenden,Jeremy Kam,Yi Yuen Wang,Tony Goldschlager,Mendel Castle-Kirszbaum; Pituitary (2025) 28:49 https://doi.org/10.1007/s11102-025-01521-4.
- Perioperative glucocorticoid supplementation in pituitary surgery; James Alexander John King,Jeremy Kam,,Tony Goldschlager,Mendel Castle-Kirszbaum; Cochrane Database of Systematic Reviews 3(3):Mar 2025
- Oral and general health quality of life following a subtemporal preauricular infratemporal approach with condylar fossa osteotomy in surgical skull base tumor resection; Seika Taniguchi, Tony Goldschalger, MendeL Castle Kirszbaum, Ryojo Akagami, Jeremy Kam; Journal of Neurosurgery 142 (2): 1-10, October 2024.
- Bilateral Optic Canal Decompression and Skull Base Resection During Transbasal Approach for Total Excision of Tuberculum Meningioma: 2-Dimensional Operative Video;Jeremy Kam, Mendel Castle Kirszbaum, David Chi Hua Tan, Michael Rizzuto; Skull Base, Surgical Video February 2025, Volume 28(2).
- Pituitary surgery and COVID; Ameen Farsakh, Sandra Li, Fidel Toomey, Mendel Castle-Kirszbaum; Pituitary 27 (6):909-915 July 2024
General Neurosurgery
- Sling technique using the superior petrosal venous complex in microvascular decompression for trigeminal neuralgia; Adrian Praeger , Hayder Al-Farttosi, Siddhanth Gujjari and Bi Yi Chen;Journal of Clinical Neuroscience, 2024-11-01, Volume 129, Article 110868
- Neurosurgery in Australia’s Top End: the lifesaving advantages of developing sustainable neurosurgical care in rural and remote regions; Oleg Peselzon, MChD,1 David Toro Tole, MD,1 Chris Rissel, PhD,2 Ameya Kamat, MBBCh,1 Liam Maclachlan, PhD,3 and Michael Redmond, MBBS1; Journal of Neurosurgery, 15 Nov 2024 Volume 142: Issue 4
Spine
- Malnutrition in Spine Oncology: Where Are We and What Are We Measuring?; Rafael De la Garza Ramos, MD1, Raphaele Charest-Morin, MD ¨ 2, C. Rory Goodwin, MD, PhD3, Scott L. Zuckerman, MD4 , Ilya Laufer, MD5 , Nicolas Dea, MD2 , Arjun Sahgal, MD6 , Laurence D. Rhines, MD7 , Ziya L. Gokaslan, MD8 , Chetan Bettegowda, MD, PhD9 , Anne L. Versteeg, MD10, Hanbo Chen, MD6, Netzer Cordula, MD11, Daniel M. Sciubba, MD12, John E. O’Toole, MD13, Michael G. Fehlings, MD, PhD14, Naresh Kumar, MD15, Alexander C. Disch, MD16, Byron Stephens, MD17, Tony Goldschlager, MBBS18, Michael H. Weber, MD, PhD19, John H. Shin, MD20; Global Spine Journal 2025, Volume 15,Issue 1 Pages: 295-465.
- A Critical Appraisal of the Application of Frailty and Sarcopenia in the Spinal Oncology Population; Mark A. MacLean, MD, MSc1, Antoinette J. Charles, BSc2 , Miltiadis Georgiopoulos, MD, PhD3, Jackie Phinney, MLIS4, Raphaele Charest-Morin, MD ¨ 5, Rory Goodwin, MD, PhD2, Ilya Laufer, MD6 , Michael G. Fehlings, MD, PhD7, John Shin, MD8 , Nicholas Dea, MD, MSc5 , Laurence D. Rhines, MD9 , Arjun Sahgal, MD10, Ziya Gokaslan, MD11, Byron Stephens, MD, MSCI12, Alexander C. Disch, MD, PhD13, Naresh Kumar, MD14, John O’Toole, MD, MS15, Daniel M. Sciubba, MD, MBA16, Cordula Netzer, MD17, Tony Goldschlager, MD, PhD18, Wende Gibbs, MD19, Michael H. Weber, MD, PhD3; Global Spine Journal 2025, Vol. 15(1S) 47S–80S.
- Advances in Surgery for Metastatic Disease of the Spine: An Update for Oncologists; Chien Yew Kow, Tony Goldschalger, MendeL Castle Kirszbaum, Jeremy Kam; Global Spine Journal Online First , July 28, 2024
Education Programs
- Fellowship: Endovascular/INR fellowships
- Senior Accredited Registrar Education: preparation for final Neurosurgery board exams
- Junior Registrar Training: Exam and interview preparation
- Senior Resident and Junior resident: Tutorial program to prepare for registrar training
- Practice Fellowship Exam
Research Facilities
- Surgical OR
- Surgical large and small animal labs
- Clinical Trials building- Hudson