Clinical Trials


Australasian Society of Infectious Diseases updated guidelines for the management of Clostridium difficile infection in adults and children in Australia and New Zealand.
Trubiano JA, Cheng AC, Korman TM, Roder C, Campbell A, May M, Blyth C, Ferguson J, Blackmore T, Riley TV, Athan E.
Int Med J 2016 [in press]

Antimicrobial surveillance of C. difficile in Australia.
Knight DR, Giglio S, Huntington PG, Korman TM, Kotsanas D, Moore CV, Paterson D, Prendergast L, Huber CA, Robson J, Waring L, Wehrhahn MC, Weldhagen GF, Wilson RM, Riley TV.
J Antimicrob Chemother. 2015 Jul 28. pii: dkv220. [Epub ahead of print]

Molecular characterization and antimicrobial susceptibilities of Clostridium difficile clinical isolates from Victoria, Australia.
Mackin KE, Elliott B, Kotsanas D, Howden BP, Carter GP, Korman TM, Riley TV, Rood JI, Jenkin GA, Lyras D.
Anaerobe. 2015 May 2. pii: S1075-9964(15)30017-2. doi: 10.1016/j.anaerobe.2015.05.001. [Epub ahead of print]

Emergence and spread of predominantly community-onset Clostridium difficile PCR ribotype 244 infection in Australia, 2010 to 2012.
Eyre DW, Tracey L, Elliott B, Slimings C, Huntington PG, Stuart RLKorman TM, Kotsiou G, McCann R, Griffiths D, Fawley WN, Armstrong P, Dingle KE, Walker AS, Peto TE, Crook DW, Wilcox MH, Riley TV
Euro Surveill. 2015 Mar 12;20(10). pii: 21059.
Diagnosis and Management of Clostridium difficile infection.

Korman TM.
Semin Respir Crit Care Med. 2015 Feb;36(1):31-43. doi: 10.1055/s-0034-1398741. Epub 2015 Feb 2.

PMID: 25643269 [PubMed – in process]

Emergence of a ribotype 244 strain of Clostridium difficile associated with severe disease and related to the epidemic ribotype 027 strain.
Lim SK, Stuart RL, Mackin K, Carter G, Kotsanas D, Francis M, Easton M, Dimovski K, Elliot B, Riley TV, Hogg G, Paul E, Korman TM, Seemann T, Stinear TP, Lyras D, Jenkin GA.
Clin Infect Dis. 2014 Apr 4. [Epub ahead of print]
PMID: 24704722 [PubMed – as supplied by publisher]

Clostridium difficile – what is the Australian story?

Johnson PD, Stuart RL.
Med J Aust. 2014 Mar 17;200(5):242-3. No abstract available.
PMID: 24641129 [PubMed – in process]

The Anti-Sigma Factor TcdC Modulates Hypervirulence in an Epidemic BI/NAP1/027 Clinical Isolate of Clostridium difficile.
Carter GP, Douce GR, Govind R, Howarth PM, Mackin KE, Spencer J, Buckley AM, Antunes A, Kotsanas D, Jenkin GA, Dupuy B, Rood JI, Lyras D.
PLoS Pathog. 2011 Oct;7(10):e1002317. Epub 2011 Oct 13.
PMID: 22022270 [PubMed – in process] Free PMC Article

Clostridium difficile laboratory testing in Australia and New Zealand: national survey results and Australasian Society for Infectious Diseases recommendations for best practice.
Ferguson JK, Cheng AC, Gilbert GL, Gottlieb T, Korman T, McGregor A, Richards M, Roberts S, Robson J, Van Gessel H, Riley TV.
Pathology. 2011 Aug;43(5):482-7. doi: 10.1097/PAT.0b013e328348c9b4.
PMID: 21716158 [PubMed – indexed for MEDLINE]

Australasian Society for Infectious Diseases guidelines for the diagnosis and treatment of Clostridium difficile infection.
Cheng AC, Ferguson JK, Richards MJ, Robson JM, Gilbert GL, McGregor A, Roberts S, Korman TM, Riley TV.
Med J Aust. 2011 Apr 4;194(7):353-8.
PMID: 21470086 [PubMed – in process]

Clostridium difficile infection: a new threat on our doorstep.
Stuart RL, Marshall C.
Med J Aust. 2011 Apr 4;194(7):331-2.
PMID: 21470079 [PubMed – in process]

ASID/AICA position statement – Infection control guidelines for patients with Clostridium difficile infection in healthcare settings.
Stuart RL Marshall C, McLaws M, Boardman C, Russo PL, Harrington G, Ferguson JK.
Healthcare Infect 2011;16(1):33-39.