The Monash Health Department of Oncology provides more than 1.5 million residents of southern Melbourne with access to world leading cancer treatment over four locations within the Monash Health service:

Moorabbin Hospital: Breast cancer, GI cancer, GU cancer, Lung cancer, Head & Neck cancer, Gynaecological cancer, Urologic cancer

Dandenong Hospital: General Oncology, Geriatric Oncology

Casey Hospital: Breast Cancer, Gynaecological Cancer

Monash Health Translation Precinct (MHTP building Level 3). Monash Medical Centre, Clayton: Cancer Clinical Trials

Monash Medical Centre Clayton: Neuro-oncology (Brain Cancer)

Our Services

Cancer patients receive care from diagnosis to treatment and follow-up support. Through collaborative multidisciplinary team framework we provide the Medical Oncology aspect of cancer care, integrating with teams from surgical and radiation oncology and Palliative and Supportive care.

Our Staff

Department Head

Prof. Eva Segelov MBBS (Hons 1) PhD FRACP
Professor/Director of Oncology
Gastrointestinal Cancers Neuroendocrine Tumours

Senior Medical Staff

Dr. Muhammad Alamgeer MBBS MD MRCP FRACP
Head and Neck Cancer

Dr. Peter Briggs MBBS FRACP
Lung Cancer

Dr. Daphne Day MBBS (Hons), FRACP
Breast, Head and Neck Cancer and Phase 1 trials

A/Prof. Michael Franco MBBS FRACP FAChPM
Palliative Medicine and Gastrointestinal Cancer

Dr. Sophia Frentzas MBBS BSc (Hons) MRCP (UK) PHD MRCP (Med Onc UK) PGDip (Oncology) FRACP
Gastrointestinal, Phase 1 Trials and Gynaecological Cancer

Dr. Geraldine Goss MBBS FRACP MD MMED
Gynaecological Cancer

A/Prof. Marion Harris MBBS FRACP
Director of Familial Cancer, Gastrointestinal and Breast Cancer

Dr Gwo Yaw Ho MBChB, BSc (Hon) FRACP
Breast Cancer, Gynaecological Cancer (Locum)

Dr. Edmond Kwan MBBS FRACP
Genitourinary Cancer

Dr. Ben Markman MBBS FRACP
Phase 1 Trials, Lung, Gastrointestinal Cancer

Dr. Sagun Parakh BSc MbChB FRACP
Phase 1 Trials, Lung Cancer and Neuro-Oncology

Dr. David Pook BMedSci (Hons) MBBS FRACP MD
Genitourinary Cancer

Dr. Ranjana Srivastava MBBS FRACP
Breast, Gastrointestinal Cancer, Geriatric Oncology

A/Prof. Andrew Strickland MBBS FRACP
Gastrointestinal Cancer

Dr. Kate Webber B.Sc (Med) MBBS (Hons 1) FRACP PhD
Breast Cancer, Gynaecological Cancer and Cancer Survivorship

Dr. Michelle White MBBS GDipPallMed FRACP
Breast Cancer

Support and Administration Staff 

Ms. Annette McClellan(Wed) and Miss. Courtney Robertson (Mon, Tues, Thu, Fri)

Oncology Department Secretary/PA to Professor Segelov.

E: PAtoProfSegelov@monashhealth.org
P: +61 3 8572 2392

Clinical Trials Fellows

Dr. Jane Yeojeong So

Dr. Caroline Lum

Advanced Trainees

Dr. Lisi Elizabeth Lim

Dr. Evangeline Samuel

Dr. Zhen Rong Siow

Dr. Rupert Strasser

Clinical Trials Research Staff

Ms. Karen Gillett
Oncology Research Manager

Ms. Merylyn Ryan
Oncology Research Operations Manager

Breast/Gynaecological

breastgynae.oncresearch@monashhealth.org

Ms. Kim Brewin
Stream Lead/Study Coordinator

Ms. Lauren Curtain
Study Coordinator

Ms. Jodie Prendergast
Study Coordinator

Early Phase

earlyphase.oncresearch@monashhealth.org

Ms. Penny MacGuire
Stream Lead/Study Coordinator

Ms. Chris Brooks
Study Coordinator

Mr. James Kinder
Study Coordinator

Lung/Other

lung.oncresearch@monashhealth.org

Ms. Laima Muceneikas
Stream Lead/Study Coordinator

Ms. Lindsay Thompson
Study Coordinator

Ms. Sally May
Study Coordinator

Gastrointestinal (GI)

gi.oncresearch@monashhealth.org

Ms. Shelley Firth
Stream Lead/Study Coordinator

Ms. Chris Poole
Study Coordinator

Ms. Michelle Zheng
Study Coordinator

Ms. Cassandra Black
Study Coordinator

Ms. Mary Kyrakides
Study Coordinator

Genitourinary (GU)

gu.oncresearch@monashhealth.org

Ms. Linda Garrett
Stream Lead/Study Coordinator

Ms. Louise Davis
Study Coordinator

Ms. Stephanie Kaladis
Study Coordinator

Ms. Deborah Chang
Study Coordinator

Ethics

Ms. Sabah Saad
Ethics Submission Specialist

Clinical Trials Assistants

Ms. Kirsty Dolan
Clinical Trials Assistant

Ms. Julie Kavanagh
Clinical Trials Assistant

Ms. Megan Gillett
Clinical Trials Assistant

Ms. Melinda Moss
Clinical Trials Assistant

Ms. Sarah Niazmand
Clinical Trials Assistant

Laboratory Assistants

Ms. Susan Alford
Laboratory Assistant

Ms. Dixita Desai
Laboratory Assistant

Oncology Finance Assistants

Ms. Emma Hoja
Oncology Research Finance Assistant

Nurse Practitioners

Ms. Gillian Kruss – Metastatic Breast Cancer

Ms. Vicki McLeod

Ms. Katie Evans – McGarth Foundation Breast Cancer Nurse

Translational Research Staff

Oncology Translational Research Group

Prof. Eva Segelov MBBS (Hons 1) PhD FRACP
Group Leader

Dr. Sophia Frentzas MBBS BSc (Hons) MRCP (UK) PHD MRCP (Med Onc UK) PGDip (Oncology) FRACP
Clinician Researcher

Dr Gwo Yaw Ho MBChB, BSc (Hon) FRACP
Clinician Researcher

Dr. Daphne Day MBBS (Hons), FRACP
PhD Student

Dr. Sameer Greenall PhD, BSc (Hons)
Research Fellow

Mr. Cameron Naidu MBBS
Honours Student 2018

 

Department Publications

2019

Athauda A, Segelov. E, Khan Z, Chau I. 2018. Integrative molecular analysis of colorectal cancer and gastric cancer: what have we learnt? Cancer Treatment Reviews. Cancer Treatment Reviews.  1 Feb 2019, 73, p. 31-40

D. Day, S. Frentzas, C. A. Naidu, E. Segelov and M. Green. Current Utility and Future Applications of ctDNA in Colorectal Cancer , IntechOpen, DOI: 10.5772/intechopen.82316.

 

2018

MacIntyre CR., Costantino V, Chen X, Segelov E, Chughtai, A, Kelleher A, Kunasekaran, M, Lane JM. 2018. Influence of population immunosuppression and past vaccination on smallpox reemergence. Emerging Infectious Diseases. 24:4:646-653.

Chin-Lenn L, Segelov E, De Boer RH, Marx GM, Hughes TM, McCarthy NJ, White S, Foo SS, Rutovitz JJ, Della-Fiorentina S, Jennens R, Antill YC, Tsoi D, Cronk MF, Lombard JM, Kiely BE, Chirgwin JH, Mann B. 2018. “The impact and indications for Oncotype DX on adjuvant treatment recommendations when third‐party funding is unavailable.” Asia‐Pacific Journal of Clinical Oncology (2018).

Shapiro, S. Thayaneswaran, C. Underhill, K. Robledo, C. Karapetis, F. Day, L. Nott, J. Jefford, L. Chantrill, N. Pavlakis, N. Tebbutt, T. Price, M. Khasraw, G. V. Hazel, P. Waring, S. Tejpar, J. Simes, V. Gebski, J. Desai, E. Segelov. Cetuximab alone or with irinotecan for refractory KRAS-, NRAS-, BRAF- and PIK3CA-wild-type metastatic colorectal cancer: the AGITG randomised phase II ICECREAM study. Clinical Colorectal Cancer, 2018, Jun 8.

Singh S, Moody L, Chan D, Metz D, Strosberg J, Asmis T, Bailey D, Bergsland E, Brendtro K, Carroll R, Cleary S, Kim M, Kong G, Law C, Lawrence B, McEwan S, McGregor C, Michael M, Pasieka J, Pavlakis N, Pommier R, Soulen M, Wyld D, Segelov E. Follow-up recommendations for completely resected gastroenteropancreatic neuroendocrine tumours. JAMA Oncology(2018) July 26.

Tang M, Price T, Shapiro J, Gibbs P, Haller D, Arnold D, Peeters M, Segelov E, Roy A, Tebbutt N, Pavlakis N, Karapetis C, Burge M. 2018. Targeted therapies for metastatic colorectal cancer. Expert Review in Anticancer Therapy 18.10(2018): 991-1006

Tang M, Price JT, Shapiro J, Gibbs P, Haller DG, Arnold D, Peeters M, Segelov E, Roy A, Tebbutt N, Pavlakis N, Karapetis C, Burge M. Adjuvant therapy for resected colon cancer 2017, including the IDEA analysis (2018). Expert Review of Anticancer Therapy. Volume 18(4), 339-349.

Singh S, Chan DL, Moody L, Liu N, Fischer HD, Austin PC, Segelov E. Recurrence in Resectable Gastroenteropancreatic Neuroendocrine Tumors. JAMA Oncol. 2018;4(4): 583-585.

Lee CK, Scott C, Lindeman GJ, Hamilton A, Lieschke E, Gibbs E, Asher R, Badger H, Paterson R, Macnab L, Kwan EM, Francis P, Boyle F, Friedlander M. Phase 1 trial of olaparib and oral cyclophosphamide in BRCA breast cancer, recurrent BRCA ovarian cancer, non-BRCA triple-negative breast cancer, and non-BRCA ovarian cancer. Br J Cancer 2018. In Press

Ha FJ, Spain L, Dowling A, Kwan EM, Pezaro C, Day D, Chia PL, Tran B, Pook D, Weickhardt AJ. Timing of Brain Metastases Development in Metastatic Renal Cell Cancer patients treated with Targeted Therapies and Survival Outcomes: an Australian Multicentre Study. Asia Pac J Clin Oncol 2018. In Press

Fettke HC*, Kwan EM*, Azad AA. Cell-free DNA in cancer: current insights. Cell Oncol (Dordr). In Press * Co-first author

C. J. McLaren., D. Day., D Croagh., A. Strickland., E. Segelov: Endoscopic Ultrasound in Pancreatic Cancer. Advances in Pancreatic Cancer, 09/2018; , ISBN: 978-1-78923-640-8, DOI:10.5772/intechopen.75211

P. Gibbs., V. Heinemann., N. K. Sharma., J. Taieb., J. Ricke., M. Peeters., M. Findlay., B. Robinson., C. Jackson., A. Strickland., V. Gebski., M. Van Buskirk., H. Zhao., G. Van Hazel: Effect of Primary Tumor Side on Survival Outcomes in Untreated Patients With Metastatic Colorectal Cancer When Selective Internal Radiation Therapy Is Added to Chemotherapy: Combined Analysis of Two Randomized Controlled Studies. Clinical Colorectal Cancer 06/2018;, DOI:10.1016/j.clcc.2018.06.001

K. Shitara., M. Özgüroğlu., Y. Bang., M. Di Bartolomeo., M. Mandalà., M. Ryu., L. Fornaro., T. Olesiński., C. Caglevic., H. C Chung., K. Muro., E. Goekkurt., W. Mansoor., R. S McDermott., E. Shacham-Shmueli., X. Chen., C. Mayo., S. P. Kang., A. Ohtsu., C. S Fuchs., G. Lerzo., J. M. O’Connor., G. A. Mendez., J. Lynam., N. Tebbutt., M. Wong., A. Strickland., et al: Pembrolizumab versus paclitaxel for previously treated, advanced gastric or gastro-oesophageal junction cancer (KEYNOTE-061): a randomised, open-label, controlled, phase 3 trial. The Lancet 06/2018; 392(10142)

M. G. Lawrence., D. Obinata., S. Sandhu., L. A. Selth., S. Q. Wong., L. H. Porter., N. Lister., D. Pook., et al. Patient-derived models of abiraterone-and enzalutamide-resistant prostate cancer reveal sensitivity to ribosome-directed therapy. European urology 74 (5), 562-572 (2018)

Sarah Q. To, Edmond M. Kwan, Heidi C. Fettke, Andrew Mant, Maria M. Docanto, Luciano Martelotto, Patricia Bukczynska, Nicole Ng, Lisa-Jane K. Graham, Phillip Parente, Carmel Pezaro, Kate Mahon, Lisa Horvath, Tilman Todenho¨fer, Arun A. Azad. Expression of Androgen Receptor Splice Variant 7 or 9 in WholeBlood Does Not Predict Response to Androgen-Axis–targeting Agents in Metastatic Castration-resistant Prostate Cancer Eur Urol 2018. doi: 10.1016/j.eururo.2018.01.007. [Epub ahead of print]

Au L, Grant M, Haydon A, Segelov E, Antill Y, Oliva, Wilkins S, P McMurrick P, J Shapiro J. 2018. Immunohistochemistry testing for mismatch repair deficiency in Stage 2 colon cancer: a cohort study of two cancer centres. International Journal of Surgery. 51:71-5.

Chi, W, Warner R, Chan D, Singh S, Segelov E, Strosberg J, Wisnivesky J, Kim M. 2018. Long-term Outcomes of Gastroenteropancreatic Neuroendocrine Tumors. Pancreas. 47:321-25.

Chan DL, Moody L, Segelov E, Metz D, Strosberg J, Pavlakis N, Singh S. Follow-up for resected gastroenteropancreatic neuroendocrine tumours (GEP-NETs): A practice survey of the Commonwealth Neuroendocrine collaboration (CommNETs) and the North American Neuroendocrine Tumor Society (NANETS). Neuroendocrinology, 2018.

S. R. Davis., P. J. Robinson., F. Jane., S. White., M. White., R. J. Bell. Intravaginal Testosterone Improves Sexual Satisfaction and Vaginal Symptoms Associated With Aromatase Inhibitors. The Journal of Clinical Endocrinology & Metabolism. November 2018, Volume 103(11), 4146-4154.

K. D. Marini., D. R. Croucher., R. A. McCloy., V. Vaghjiani, A. Gonzalez-Rajal, J. F. Hastings, V. Chin, A. Szczepny, K. Kostyrko, C. Marquez, W. S. N. Jayasekara., M. Alamgeer., V. Boolell., J. Z. R. Han., T. Waugh., H. C. Lee., S. R. Oakes., B. Kumar., C. A. Harrison., M. P. Hedger., N. Lorensuhewa., B. Kita., R. Barrow., B. W. Robinson., D. M. de Kretser, J. Wu., V. Ganju, E. A. Sweet-Cordero, A. Burgress, L. G. Martelotto, F. J. Rossello, J. E. Cain, D. N. Watkins. Inhibition of activing signalling in lung adenocarcinoma increase the therapeutic index of platinum chemotherapy. Sci Transl Med (10), 2018.

T. L. Leong., V. Gayevskiy., D. P. Steinfort., M. R. De Massy., A. Gonzalez-Rajal., K. D. Marini., E. Stone., V. Chin., A. Havryk., M. Plit., L. B. Irving., B. R. Jennings., R. A. McCloy., W. S. N. Jayasekara., M. Alamgeer., V. Boolell., A. Field., P. A. Russell, B. Kumar., D. J. Gough., A. Szczepny., V. Ganju., F. J. Rossello., J. E. Cain., A. T. Papenfuss., M. Asselin-Labat., M. J. Cowley., D. N. Watkins. Deep multi-region whole-genome sequencing reveals heterogeneity and gene-by-environment interactions in treatment-naïve, metastatic lung cancer. Oncogene, 2018

2017

Segelov E, Lordick F, Goldstein D, Chantrill L, Croagh D, Lawrence B, Arnold D, Chau I, Obermannova R, Price T. 2017. Current challenges in optimizing systemic therapy for patients with pancreatic cancer: Expert perspectives from the Australian Gastrointestinal Trials Group with invited international faculty. Expert Review in Anticancer Therapy. 17:951-64. First author, Impact factor 2

Wein L, Rowe C, Brady B, Handolias D, Lipton L, Pook D, Stanley R, Haines I. Prevalence of systemic anticancer therapy for patients within the last 30 days of life: experience in a private hospital oncology group. Internal medicine journal. 2017 Mar 1;47(3):280-3.

Srivastava R. The Interpreter. N Engl J Med. 2017 Mar 2;376:812-3

Chan DLH, Segelov E, Wong RSH, Smith A, Herbertson RA, Li B, Tebbutt N, Price T, Pavlakis N. Epidermal growth factor receptor (EGFR) inhibitors for metastatic colorectal cancer. Cochrane Database of Systematic Reviews 2017 Issue 6, Art: CD007047. Contributing author, impact factor 6.1

Lam M, Tran B, Beck S, Tie J, Herath D, Whittle J, Kwan EM, Fox S, Fellowes A, Ananda S, Lipton L, Gibbs P, Rosenthal M, Desai J. (in press). Precision medicine using a clinician-directed, tailored approach to molecular profiling. Asia Pac J Clin Oncol. doi: 10.1111/ajco.12787

Chan D, Segelov E, Ferone D, Albertelli M, Pavlakis N, Singh S. 2017. Escalated dose somatostatin analogues for anti-proliferative effect in GEP-NETS: A systematic review. Endocrine. 57:366-75. contributing author, Impact factor 3.1

Roy AC, Wattchow D, Astill D, Singh S, Pendlebury S, Gormly K, Segelov E. 2017. Uncommon anal neoplasms in Surgical Clinics of North America. Surgical Oncology Clinics of North America 26:143-61. Invited chapter editor and Senior author, Impact factor 2

Chan D, Segelov E, Singh S. 2017. Update on the use of everolimus in the management of metastatic neuroendocrine tumors of gastrointestinal origin. Therapeutic Advances in Gastroenterology. 10:132-41. One of three contributing authors, Impact factor 5

Sandler C, Goldstein D, Horsfield S, Bennett BK, Friedlander M, Bastick PA, Lewis CR, Segelov E, Boyle FM, Chin MTM, Barry BK, Webber K, Lloyd AR. 2017. Randomized evaluation of cognitive-behavioral therapy and graded exercise therapy for post-cancer fatigue. Journal of Pain and Symptom Management. 54:74-84. contributing author, Impact factor 2.6

Strosberg J, Halfdanarson T, Bellizzi A, Chan J, Dillon J, Heaney A, Kunz P, O’Dorisio T, Salem R, Segelov E, Howe J, Pommier R, Brendtro K, Mohammad Bashir M, Singh S, Soulen M, Tang L, Zacks J, Yao J, Bergsland E. The North American Neuroendocrine Society (NANETS) Consensus Guidelines for Surveillance and Medical Management of Midgut Neuroendocrine Tumors. Pancreas 46:707-14. contributing author, Impact factor 2.7

Kwan EM, Beck S, Amir E, Jewett MA, Sturgeon JFG, Anson-Cartwright L, Chung PWM, Warde PR, Moore MJ, Bedar PL, Tran B. (in press). Impact of granulocyte-colony stimulating factor on bleomycin-induced pneumonitis in chemotherapy-treated germ cell tumours. Clin Genitourin Cancer. doi: 10.1016/j.clgc.2017.08.012

Templeton DJ, Roberts JM, Poynten IM, Law C, Hillman RJ, Farnsworth A, Fairley CK, Tabrizi SN, Grulich AE, Jin F, Acraman B, Carr A, Carroll S, Cooper D, Cornall A, Crampton L, Fairley K, Feeney L, Fraissard E, Howard K,  & SPANC Study Team (Law M, Machalek DA, McCaffery K, McGrath P, Mellor R, Norris R, O’Dwyer M, Pendlebury S, Petoumenos K, Phillips S, Poynten IM, Prestage G, Richards ., Schema L, Seeds D,  Segelov E, Templeton M, Thurloe, JK, Tong WWY, Varma R. 2017. Prevalence and predictors of unsatisfactory anal cytology tests in a cohort of gay and bisexual men in Sydney, Australia: Baseline findings from the Study of the Prevention of Anal Cancer (SPANC). European Journal of Cancer Prevention. 26:212-16

Martinez- Chacon G, Brown KA, Docanto MM, Kumar H, Salminen S, Saarinen N, Mäkelä S. IL-10 suppresses TNF-α-induced expression of human aromatase gene in mammary adipose tissue.FASEB J.2018 Jun:32(6):3361-3370

To SQ, Kwan EM, Fettke HC, Mant A, Docanto MM, Martelotto L, Bukczynska P, Ng N, Graham LK, Parente P, Pezaro C, Mahon K, Horvath L, Todenhöfer T, Azad AA. Expression of Androgen Receptor Splice Variant 7 or 9 in Whole Blood Does Not Predict Response to Androgen-Axis-targeting Agents in Metastatic Castration-resistant Prostate Cancer. Eur Urol. 2018 Jun;73(6):818-821.

Au CC, Docanto MM, Zahid H, Raffaelli FM, Ferrero RL, Furness JB, Brown KA. Des-acyl ghrelin inhibits the capacity of macrophages to stimulate expression of aromatase in breast adipose stromal cells.J Steroid Biochem Mol Biol. 2017 Jun;170:49-53

To SQ, Kwan EM, Fettke H, Mant A, Docanto M, Martelotto L, Bukczynska P, Ng N, Graham LK, Parente P, Pezaro C, Mahon K, Horvath L, Todenhöfer T, Azad AA (2018). “AR-V7 or AR-V9 expression in whole blood does not predict response to androgen-axis targeting agents in metastatic castration-resistant prostate cancer”. European Urology. Jun;73(6):818-821

Ho SM, Rao RC, To SQ, Schoch E and Tarapore P (2017). “Bisphenol A and its analogues disrupt centrosome cycle and microtubule dynamics in prostate cancer”. Endocrine Related Cancer. Feb;24(2):83-96

For 2016 publications click here

Department Abstracts

2019

Kwan E, To S, Fettke H, Docanto M, Bukczynska P, Mant M, Waltham M, Pook D, Ng N, Graham L-J, Segelov E, Mahon K, Davis I, Parente P, Pezaro C, Horvath L, Azad A. Whole blood FOLH1 mRNA expression and treatment response in metastatic castration-resistant prostate cancer (mCRPC). Accepted for ASCO GU, Feb 2019, San Francisco

2018

Rao, S., Sclafani, F., Eng, C., Grønlie Guren, M., Adams, R.A., Benson, A., Sebag-Montefiore, D., Segelov E, Bryant, A., Peckitt, C. and Roy, A., 2018. LBA21 InterAACT: A multicentre open label randomised phase II advanced anal cancer trial of cisplatin (CDDP) plus 5-fluorouracil (5-FU) vs carboplatin (C) plus weekly paclitaxel (P) in patients (pts) with inoperable locally recurrent (ILR) or metastatic treatment naïve disease-An International Rare Cancers Initiative (IRCI) trial. Annals of Oncology, 29(suppl_8), pp.mdy424-022

La C, Segelov E, McLeod V, Grewal G. An expanded role oncology pharmacist adds value to symptom and urgent review clinics. ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY. Vol. 14. 2018.

Gan C, Gruner J, Segelov E.  Survey on patterns of travel for patients attending chemotherapy day units in Monash Health-A local experience. .ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY. Vol. 14. p113, 2018.

Lie G, Segelov E, Srivastava R. Implementation of a validated chemotherapy prediction tool in a busy oncology clinic. ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY 2018 Nov 1 Vol. 14, pp. 118-119).

Lum C, Rogers S, Sharma K, Marshall L, Sherwell S, Franco M, Hadley AM,  Segelov E, Day D. Implementation and results of the Victorian cancer patient experience survey (VCPES) at Monash Health. ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY 2018 Nov 1 Vol. 14, pp. 119-119

Blinman P, Martin A, Jefford M, Goldstein D, Boadle D, Morris M, Tebbutt N, Aiken C, Segelov E, Paul J, Haydon A. Patients’ Preferences for 3 Versus 6 Months of Adjuvant Chemotherapy (ACT) for Colon Cancer in the SCOT Trial: What Survival Benefits Make Longer Chemotherapy Worthwhile? ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY 2018 Aug 1 Vol. 14, pp. 51-51.

Super L, Nguyen H, Segelov E, McLeod V, Degraves S, Fedele P, Vandenberg K, James K. A Pathway to Improving an Adolescent and Young Adult Oncology Service: Voices of Patients and Parents. 3rd Global Adolescent & Young Adult Cancer Congress. Dec 2018, Sydney.

Segelov E,Bergsland E, Card C, Hope T, Kunz P, Laidley D, Lawrence B, Leyden S, Michael M, Modahl L, Myrehaug S, Padda S, Pommier R, Ramirez R, Soulen M, Strosberg J, Thawer  A, Wei B, Xu B,  Singh S. 2018. Pulmonary Neuroendocrine (Carcinoid) Tumors: The Commonwealth Neuroendocrine Tumour Collaboration (CommNETs) and North American Neuroendocrine Tumor Society (NANETS) Endorsement and Update of European Neuroendocrine Tumor Society (ENETS) Best Practice Consensus for Lung Neuroendocrine Tumors (LNET), Annals of Oncology. 2018 Oct 1;29(suppl 8).

Rao, S., Sclafani, F., Eng, C., Grønlie Guren, M., Adams, R.A., Benson, A., Sebag-Montefiore, D., Segelov E, Bryant, A., Peckitt, C. and Roy, A., 2018. LBA21 InterAACT: A multicentre open label randomised phase II advanced anal cancer trial of cisplatin (CDDP) plus 5-fluorouracil (5-FU) vs carboplatin (C) plus weekly paclitaxel (P) in patients (pts) with inoperable locally recurrent (ILR) or metastatic treatment naïve disease-An International Rare Cancers Initiative (IRCI) trial. Annals of Oncology, 29(suppl_8), pp.mdy424-022.

Singh, S., Bergsland, E., Card, C., Hope, T., Kunz, P., Laidley, D., Lawrence, B., Leyden, S., Michael, M., Modahl, L. and Myrehaug, S., Padda S, Pommier R, Ramirez R, Soulen M, Strosberg J, Thawer A, Wei B, Xu B, Segelov E. 2018. P1. 12-06 Pulmonary Neuroendocrine (Carcinoid) Tumors: CommNETs/NANETS Endorsement and Update of the ENETs Best Practice Consensus. Journal of Thoracic Oncology, 13(10), p.S575.

La C, Segelov E, McLeod V, Grewal G. An expanded role oncology pharmacist adds value to symptom and urgent review clinics. Accepted for COSA 2018 Nov, Perth.

Gan C, Gruner J, Segelov E. Survey on patterns of travel for patients attending chemotherapy day units in Monash Health- a local experience. Accepted for COSA 2018 Nov, Perth.

Super L, Nguyen H, Segelov E, McLeod V, Degraves S, Fedele P, Vandenberg K, James K. A Pathway to Improving an Adolescent and Young Adult Oncology Service: Voices of Patients and Parents. Accepted for 3rd Global Adolescent & Young Adult Cancer Congress. Dec 2018, Sydney.

Segelov E, Williams D, Chia J, Sieber O. COX2 and HLA immunohistochemical (IHC) staining in colorectal tumour samples from patients participating in the ASCOLT clinical trial of adjuvant aspirin therapy. Journal Clinical Onc 36 (4_suppl), 695-695.

Clarke S, Burge M, Feeney K, Jones K, Gibbs P, Molloy M,Marx G, Price T, Reece W, Segelov E, Tebbutt N. Results from an Australian translational study to evaluate the prognostic role of inflammatory markers in patients with mCRC treated with bevacizumab. Journal Clinical Onc 36 (4_suppl), 719-719. Presented at ASCO GI 2018.

Blinman, D. Goldstein, A. Martin, M. Jefford, D. Boadle, N. Tebbutt, J. Paul, A. Haydon, E. Segelov, M. Stockler. Patients’ preferences for 3 months versus 6 months of adjuvant chemotherapy (ACT) for colon cancer in the SCOT trial: what survival benefits make longer chemotherapy worthwhile? J Clin Oncol (2018) 36:15_suppl: 3602-3602.

Singh S, Bergsland E, Card C, Hope T, Kunz P, Ladiley D, Lawrence B, Leyden S, Michael M, Modahl L, Myrehaug S, Padda S, Pommier R, Ramirez R, Soulen M, Strosberg J, Thawer A, Wei B, Xu B, Segelov E. Pulmonary Neuroendocrine (Carcinoid) Tumors: CommNETs/NANETS Endorsement and Update of the ENETs Best Practice Consensus, IASLC 19th World Conference on Lung Cancer Sept 2018, Toronto.

Segelov E, Bergsland E, Card C, Hope T, Kunz P, Ladiley D, Lawrence B, Leyden S, Michael M, Modahl L, Myrehaug S, Padda S, Pommier R, Ramirez R, Soulen M, Strosberg J, Thawer A, Wei B, Xu B, Singh S. Pulmonary Neuroendocrine (Carcinoid) Tumors: The Commonwealth Neuroendocrine Tumour Collaboration (CommNETs) and North American Neuroendocrine Tumor Society (NANETS) Endorsement and Update of European Neuroendocrine Tumor Society (ENETS) Best Practice Consensus for Lung Neuroendocrine Tumors (LNET), European Society of Medical Oncology, Oct 2018, Munich.

M. Alamgeer., D. N. Watkins., I. Banakh., B. Kumar., D. J. Gough., B. Markman., Vinod Ganju. A phase IIa study of HA-irinotecan, formulation of hyaluronic acid and irinotecan targeting CD44 in extensive-stage small cell lung cancer. Investigational New Drugs (2018) 36:288-298

Kwan EM, Semira M, Muttiah C, Beck S, Anton A, Tran B. Changing treatment landscape in the initial management of metastatic castrate-resistant prostate cancer (mCRPC): an Australian multi-centre retrospective study, Oral Abstract Presentation, MOGA Annual Scientific Meeting, 2018. Adelaide, Australia.

Fettke HC, Kwan EM, Mant A, Docanto MM, Bukczynska P, To SQ, Waltham M, Ng N, Parente P, Pezaro C, Azad AA. Plasma cell-free DNA concentration and outcomes in metastatic castrate-resistant prostate cancer patients treated with androgen receptor signalling inhibitors, Oral Abstract Presentation, ANZUP Annual Scientific Meeting, 2018. Sydney, Australia. * Selected for “Best of the Best” session

Kwan EM, To SQ, Fettke HC, Mant A, Docanto MM, Martelotto L, Bukczynska P, Ng N, Graham LK, Parente P, Pezaro C, Mahon K, Horvath L, Todenhofer T, Azad AA. Whole blood AR-V7 and AR-V9 mRNA expression and treatment response in metastatic castrate-resistant prostate cancer, Poster Presentation, ASCO GU, 2018. San Francisco, USA. * Conquer Cancer Foundation Merit Award

L. Gulley, M. Borre, N. J. Vogelzang, S. Ng, N. Agarwal, C. C. Parker, D. W. Pook, P. Rathenborg, T. W. Flaig, J. Carles, N. D. Shore, L. Chen, C. R. Heery, W. R. Gerritsen, F. Priou, P. W. Kantoff. Results of PROSPECT: A randomized phase 3 of PROSTVAC-V/F (PRO) in men with asymptomatic or minimally symptomatic metastatic, castration-resistant prostate cancer. J Clin Oncol (2018) 36:15_suppl, 5006-5006.

Michael, D. W. Pook, V. Ganju, E. Link, G. C. Toner, R. J. Hicks, A. Matera, M. Thompson, C. Cullinane, I. Campbell, M. Burge, C. S. Karapetis. The utility of genomics and functional imaging to predict Sunitinib PK and PD: The Predict SU study. J Clin Oncol 36, 2018 (suppl; abstr 2563).

Desai, M. Voskoboynik, B. Markman, J. Hou, D. Zeng, T. Meniawy. Phase 1/2 study investigating safety, tolerability, pharmacokinetics, and preliminary antitumor activity of anti-PD-L1 monoclona antibody bgb-A333 alone and in combination with anti-PD-monoclonal antibody tislelizumab in patients with advanced solid tumors. J Clin Oncol 36, 2018 (suppl; abstr TPS3113).

2017

Segelov E, Earle C, Venook A, Saskin R, Mofid L, Singh S. 2017. Survival by sidedness of metastatic colorectal cancer (mCRC) treated with Epidermal Growth Factor Receptor Antibodies (EGFR-Ab) in the refractory setting: a population-based study of 1509 patients. Annals of Oncology 28.suppl_5.

Singh S, Moody L Chan DL, Metz D, Strosberg J, Segelov E. 2017. Follow up recommendations for completely resected Gastroenteropancreatic Neuroendocrine Tumours (GEP-NETs): Consensus Guidelines from the Commonwealth Neuroendocrine Tumour Collaboration (CommNETS) in conjunction with the North American Neuroendocrine Tumour Society (NANETS). Annals of Oncology 28.suppl_5 (2017)

Chan DL, Segelov E, Moody L, Liu N, Fischer H, Austin P, Singh S. 2017. Follow-up and recurrence in resected gastroenteropancreatic neuroendocrine tumours: A population-based study. Annals of Oncology 28.suppl_5

Shapiro J, Thavaneswaran S, Waring P, Desai J, Mann K, Elez E, Chantrill L, Pavlakis N, Nott L, Underhill C, Khasraw M, Wasan H, Ciardiello F, Jefford M, Joubert W, Haydon A, Karapetis C, Price T, Wilson K, Segelov E. 2017. The AGITG ICECREAM STUDY: The Irinotecan Cetuximab Evaluation and Cetuximab Response Evaluation Amongst Patients with a G13D Mutation- analysis of outcomes in patients with “Quad WT”. J Clin Oncol 35 (15) 3572.

Segelov E, Chan DL, Moody L, Metz D, Strosberg J, Singh S. 2017. Development of follow up recommendations for completely resected Gastroenteropancreatic Neuroendocrine Tumours (GEP-NETS): Practice Survey of Commonwealth Neuroendocrine Tumour Collaboration (CommNETS) in conjunction with North American Neuroendocrine Tumour Society (NANETS). ASCO GI 2017 (oral presentation). Journal Clin Onc (2017): 424-424.

Chan DL, Segelov E, Ferone D, Albertelli M, Singh S. 2017. Escalated dose somatostatin analogues (SSAs) in management of neuroendocrine tumors (NETs): A systematic review. Journal Clin Onc (2017): 422-422

Moody L, Segelov E, Chan D. Carsley S, Strosberg J, Metz D, Singh S. 2017. Optimising followup after complete surgical resection of Gastrointestinal Neuroendocrine Tumours- a Delphi process to produce expert consensus in an area lacking clinical evidence. NEUROENDOCRINOLOGY, vol. 105, pp. 336-336. Neuroendocrinology 2017.105: 336-336.

Segelov E, Chan DL, Moody L, Metz D, Strosberg J, Singh S. 2017. Follow-up in resected gastroenteropancreatic neuroendocrine tumours. AGITG Annual Scientific Meeting, Cairns 2017.

S. Menon., M. Alamgeer. Incidence of Unplanned Admissions During Chemotherapy for Head and Neck and Lung Cancers. Asia-Pacific Journal of Clinical Oncology 13, 131-131 (2017).

C. Muttiah., M. Alamgeer. Retrospective Analysis of Thoracic Oncology at Monash Health 2016-2017 Specifically Investigating Prevalence of EGFR Mutated Lung Cancers. Asia-Pacific Journal of Clinical Oncology 13, 162-162 (2017)

L. Marshall., C. Giddings., A. Coleman., M. A. Silvers., M. Alamgeer. Head and Neck Cancers Audit of Chemotherapy at Monash Cancer Centre. Asia-Pacific Journal of Clinical Oncology 13, 186-186 (2017)

D. M. Jiang., H. Sim., L. L. Siu., J. D. Shapiro., G. Liu., T. J. Price., D. J. Jonker., C. S. Karapetis., A. Strickland., W. Zhang., M. Jeffery., D. Tu., S. Ng., S. S. Sabesan., J. Shannon., A. R. Townsend., E. Morgen., W. Xu., C. J. O’Callaghan., E. X. Chen: Cetuximab (Cet) clearance and survival in patients (pts) with metastatic colorectal cancer (mCRC).. Journal of Clinical Oncology 05/2017; 35(15_suppl):3600-3600.

Desai, B. Markman, S. Ananda, N. C. Tebbutt, M. Michael, B. J. Solomon, G. A. McArthur, J. Lundy, E. M. Kwan, P. M. Waring, B. Tran. (2017). A phase I/II trial of combined BRAF and EGFR inhibition in patients (pts) with BRAF V600E mutated (BRAFm) metastatic colorectal (mCRC): The EViCT (Erlotinib and Vemurafenib in Combination Trial) study. J Clin Oncol 35, 2017 (suppl; abstr 3557)

Poon P, Shaw T, Franco M, Runacres F, William L, Yoong J. Successful large volume ‘lymphocentesis’ for refractory lymphoedema in lower and upper limbs. Internal Medicine Journal. 2017 May 1;47(5):607-.

Lee B, Cohen J, Lipton L, Tie J, Javed A, Li , Goldstein D, Cooray P, B Nagrial A, Burge M, Tebbutt N, Nikfarjam M, Harris M, O’Broin-Lennon, Wolfganag C, TomasettiC, Papadopoulos NJ, Kinzler K, Vogelstein B, Gibbs P. Potential role of circulating tumour DNA( ctDNA) in the early diagnosis and post-operative management of localised pancreatic cancer. ASCO GI 2017 Abs 4101

Cubillo A, dean A, Munoz A, Pazo Cid R, Martin M, Mercade T, Lipton L, Harris M, Santasusana J, Gullen C, Tebbutt N, Cooray P, Sohal D, Zalupski M, Kolevska T, Stagg R , Holmgren E, Goldstein D. Yosemite : A 3 arm Double blind randomised Phase 2 study of Gemcitabine , Abraxane amd Placebo versus Gemcitabine , Abraxane and either 1 or 2 truncated courses of Demcizumab .620 PD ESMO 2017

Jong I, Croagh D, Harris M, Bradney M. Biodistribution of implanted phosphorus -32 into unresectable locally advanced pancreatic adenocarcinoma given in combination with gemcitabine +nab-paclitaxel chemotherapy – A single centre experience. World Federation of Nuclear Medicine and Biology Congress 2018 Abstract 1745. Accepted December 2017

For 2017 Meeting Abstracts and Posters click here

Updated February 2019