MBBS (Hons) BMedSci (Hons) (Monash) FRACP PhD (Monash)

Infectious Diseases Physician
Physician, Refugee Health Service

Other:
ARC Centre of Excellence in Structural and Functional Microbial Genomics, Monash University

Publications
The PTEN and Myotubularin Phosphoinositide 3-Phosphatases: Linking Lipid Signalling to Human Disease.
Leslie NR, Davies EM, Sheffield DA, Tibarewal P, Fedele CG, Mitchell CA.
Subcell Biochem. 2012;58:281-336.

Silencer of death domains (SODD) inhibits skeletal muscle and kidney enriched inositol phosphatase (SKIP) and regulates phosphoinositide 3-kinase (PI3K)/Akt signalling to the actin cytoskeleton.
Rahman P, Huysmans RD, Wiradjaja F, Gurung R, Ooms LM, Sheffield DA, Dyson JM, Layton MJ, Sriratana A, Takada H, Tiganis T, Mitchell CA.
J Biol Chem. 2011 Jun 28. [Epub ahead of print]
PMID: 21712384 [PubMed – as supplied by publisher] Free Article

The myotubularin phosphatase MTMR4 regulates sorting from early endosomes.
Naughtin MJ, Sheffield DA, Rahman P, Hughes WE, Gurung R, Stow JL, Nandurkar HH, Dyson JM, Mitchell CA.
J Cell Sci. 2010 Sep 15;123(Pt 18):3071-83. Epub 2010 Aug 24.
PMID: 20736309 [PubMed – as supplied by publisher]

Regulation of PI(3)K/Akt signalling and cellular transformation by inositol polyphosphate 4-phosphatase-1.
Ivetac I, Gurung R, Hakim S, Horan KA, Sheffield DA, Binge LC, Majerus PW, Tiganis T, Mitchell CA.
EMBO Rep. 2009 May;10(5):487-93. Epub 2009 Mar 27.
PMID: 19325558 [PubMed – indexed for MEDLINE]Free PMC ArticleFree text

Characterisation of PfRON6, a Plasmodium falciparum rhoptry neck protein with a novel cysteine-rich domain.
Proellocks NI, Kats LM, Sheffield DA, Hanssen E, Black CG, Waller KL, Coppel RL.
Int J Parasitol. 2009 May;39(6):683-92. Epub 2008 Nov 27.
PMID: 19073187 [PubMed – indexed for MEDLINE]

Differential occurrence of mutations in mitochondrial DNA of human skeletal muscle during aging.
Zhang C, Liu VW, Addessi CL, Sheffield DA, Linnane AW, Nagley P.
Hum Mutat. 1998;11(5):360-71. Erratum in: Hum Mutat 1998;12(1):69.
PMID: 9600454 [PubMed – indexed for MEDLINE

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